More secure to use e.g. Services in Rambo than in browser or native clients?

Same question is asked for More secure to use e.g. Whatsapp Web in Franz than in browser? [closed].

On its answer it is said that:

No, Franz is not inherently more secure than a regular browser.

In an ordinary web application the impact of this XSS flaw would have been restricted to that particular domain, but in a desktop application it endangers the host itself.

On its answer’s comment it is mentioned that is an open source alternative.

==> I was wondering would is secure to use like a regular browser or their native clients? or does it have any security holes like Franz has?