For example I cannot switch between the tabs in gnome-terminal with Alt+1, Alt+2 anymore. Shortcuts in general and Menu shortcuts specifically, are enabled via the global gnome-terminal settings.
When I hit Alt + 1 it looks like this, and it’s the same behaviour without tmux:
I already opened an issue in the gnome-terminal repo, but it was rejected. It really decreases the usability of the gnome-terminal for me.
I’d be happy to find any solution to that, even if it requires a bit of effort.