What pacing problems for the DM does Murder in Baldur’s Gate pose when running the adventure?

This question is directed at DM/GMs who have run the adventure Murder in Baldur’s Gate.

I am prepping to run this adventure, and it seems that this module’s ten phase / three faction plot structure makes for a variety of player and DM decision points and interaction with arbitrary sized groups of NPCs.

My objective is to do pre-emptive decision point preparation so that encounter size, pace, timing and CR all fit the plot. I’d like to use lessons learned from those who have run this adventure by identifying those points that most often slowed play down. (Once identified, mitigation can be applied).

I intend to run this in D&D 5e, but experience with pacing issues and their resolution in a 4e or 3.5 context should be highly relevant and are acceptable as answers.

If, as a DM, you ran this module/adventure during or after the playtest:

What pacing/adventure flow problems did you encounter as a DM when running the adventure, and how did you resolve them?

When does the spin-off board game “Betrayal at Baldur’s Gate” take place in the Forgotten Realms setting?

The board game Betrayal at Baldur’s Gate is set in the Forgotten Realms universe in the city of Baldur’s Gate. The description leads with “The Shadow of Bhaal has come over Baldur’s Gate”. I assume the game probably isn’t officially canon (or is it?), but could the events which take place within the game with its references to Forgotten Realms’ deities, spells, weapons, events and characters be introduced into a canon Forgotten Realms campaign?

The Question

I would like to incorporate some of the events (obviously not city-destroying, or otherwise game-breaking) into a current Dungeons and Dragons (5e) game, set after the events of the Lost Mine of Phandelver adventure (1481).

When are the events that take place during Betrayal at Baldur’s Gate supposed to have taken place in the Forgotten Realms’ timeline? Or when could they have taken place if the events are not strictly canon?