When do held-items take effect?

Specifically things like the Flame Orb and Toxic Orb. The only text I could find regarding how these items work says that it

Induces [Burn/Poison] on holder. Off-Hand Item for Trainers. Standard Action to drop.

In the regular games, this only takes effect at the end of the holder’s turn. Does this work the same in PTU? If so, how does this interact with time outside of combat, where ‘turns’ don’t exist but 10-second intervals obviously still pass.